Clinical ReviewPublished April 14, 2026 · Updated 2 days ago · 8 min read

We Tested 4 Online ED Treatments for 30 Days. One Clearly Outperformed the Rest.

Most men who try the standard ED pill end up quietly disappointed, and most assume that is simply how it goes from here. It is not. We put the four most-advertised online brands through a 30-day head-to-head, with a primary care physician reviewing the results, to find out which one actually delivers and why so many men get let down by the rest.

Sarah Chen
By Sarah Chen, Editor-in-Chief
April 14, 2026
Dr. Marcus Hale
Medically reviewed by Dr. Marcus Hale, MD
✓ Verified physician reviewer
Our tester compared four online ED treatments over 30 days.
Our tester ("David," 54) compared four of the most-advertised online ED treatments over 30 days.

David did not tell his wife of 32 years why he had stopped initiating sex. He told us.

Six months earlier, he had tried Viagra for the first time. It worked, mechanically. But the 30-minute wait killed every spontaneous moment, and the headaches made it feel like a punishment. Cialis was hit or miss. And even when the physical side cooperated, something was still off. The desire, the pull, the part of him that used to want it without thinking, was not showing up. At 54 and otherwise healthy, David was quietly resigning himself to a sexless second half of his marriage.

Like a lot of men, David had been seeing the ads for months. Ro Sparks. Hims. BlueChew. Taurus. The same promises on repeat in his feed, each one certain it was the answer, none of them ever quite convincing him to click. But after half a year of avoiding his own bedroom, he was done guessing which one, if any, actually did what it claimed. So he came to us. We agreed to help him settle it the only way that would: test the four most-advertised options side by side, over 30 days, and see what held up. What we found surprised all of us, including the physician we brought in to help.

One note before we get into it. We paid for all four products ourselves and had no relationship with any of the brands when we started. Nobody knew which one would come out on top, including us.

Common Questions Before We Tested

Before David agreed to test anything, he had three questions. If you have ever thought about trying one of these, they are almost certainly the same three running through your head. The answers shaped how we set up the test.

Q: Are these online ED brands legit, or just clever marketing?

David's first question was the obvious one: how is it possible to get a real prescription medication from a website? The short answer is that telehealth is now a mainstream part of US healthcare. All four brands we tested operate through US-licensed prescribing clinicians and partnered compounding or retail pharmacies, using the same FDA-regulated active ingredients dispensed in a traditional doctor's office.[5] Where they differ is in formulation, delivery format, and price.

Q: Is it safe to take medication prescribed by a clinician you have never met in person?

This was the one Dr. Hale wanted to answer directly. As he put it:

"For straightforward erectile dysfunction, without a complicating cardiac history or contraindicated medications, an asynchronous online evaluation is medically appropriate. The screening questions these brands use cover the same criteria I use in clinic. The time saved by skipping an in-person visit is real, and for a lot of men it is the difference between getting treatment and never bringing it up at all."
— Dr. Marcus Hale, MD

Q: Do compounded medications work as well as brand-name Viagra or Cialis?

Compounded medications use the same FDA-approved active ingredients as their branded counterparts. The difference is in how they are combined, dosed, and delivered. A compounded sublingual liquid containing sildenafil and tadalafil is, pharmacologically, the same molecules a Pfizer Viagra tablet contains. What you pay more or less for is not the molecule. It is the formulation, the delivery format, and the marketing budget.

What Actually Matters in an ED Treatment

Erectile dysfunction has two primary biological causes: reduced blood flow to the penis, and impaired arousal signaling from the brain. Most prescription ED medications, sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra), address only the first.[3]

They work by inhibiting an enzyme called PDE5, which relaxes blood vessels and increases blood flow. For many men, that is enough.

But for many others, particularly men over 40, the issue is not purely circulatory. Stress, anxiety, performance pressure, and natural changes in dopamine signaling can blunt arousal even when blood flow is medically restored.

If you have taken an ED pill and thought, it worked, but something still was not there, you are not imagining it, and you are not broken. You were likely treating only half of what was actually going on.

"PDE5 inhibitors do one thing well. They improve blood flow. But they do not directly address libido or the mental side of arousal. For patients struggling with both, that is a real gap."
— Dr. Marcus Hale, MD

That is why the most complete ED treatments address four things, not one:

  • Physical blood flow
  • Mental arousal and dopamine signaling
  • Fast onset, so the moment is not lost
  • Discreet, easy delivery

As you will see in the results, only one of the four checked all four boxes. Why it could is the part worth reading.

How We Tested

Over 30 days, our tester used each of the four products in randomized order, with at least 72 hours between doses. We tracked four things: time to onset, perceived effectiveness (rated 1 to 10 by the tester), side effects, and ease of use.

We also brought in Dr. Marcus Hale, a board-certified primary care physician with more than 15 years treating men's sexual health, to evaluate each product's formulation from a clinical standpoint.

The four products were the most-advertised online ED treatments available without an in-person visit, each in the most-prescribed dose the brand offers.

The four ED treatments tested, laid flat
The four ED treatments tested: Taurus CHARGE, Ro Sparks, Hims Hard Mints, and BlueChew Max.

Side-by-Side Comparison

Taurus CHARGE
★ Editor's Pick
Active Ingredients
Sildenafil + Tadalafil + Vardenafil + PT-141
Form
Sublingual liquid
Time to Onset
10-15 minutes
Duration
Up to 36 hours
Price per Dose
$12
Tester Score
9.4 / 10
Ro Sparks
Active Ingredients
Sildenafil + Tadalafil
Form
Sublingual tablet
Time to Onset
15 minutes
Duration
Up to 36 hours
Price per Dose
$12
Tester Score
7.8 / 10
Hims Hard Mints
Active Ingredients
Sildenafil + Tadalafil + B12
Form
Chewable
Time to Onset
30-60 minutes
Duration
Up to 36 hours
Price per Dose
$7.50
Tester Score
6.5 / 10
BlueChew Max
Active Ingredients
Sildenafil + Tadalafil
Form
Chewable
Time to Onset
30-60 minutes
Duration
Up to 36 hours
Price per Dose
$10
Tester Score
6.2 / 10

Green = best in class. Tester score reflects the 30-day trial across effectiveness, onset, and ease of use.

How we scored

Each product was rated on a 1-10 scale across four dimensions: time to onset, perceived effectiveness, ease of use, and side-effect profile. The Tester Score shown is a weighted average, with effectiveness double-weighted. Methodology was reviewed by Dr. Marcus Hale prior to the trial. We did not modify scores after the trial began.

Trusted Ranking Pick

Taurus CHARGE

4.7 / 5

After 30 days, one product came out ahead for a specific reason: it was the only one that treated the mental side of arousal, not just blood flow. The full explanation is in the next section.

  • Fastest onset (10-15 min)
  • Only 4-in-1 formula (the only one with a brain-arousal ingredient)
  • Most discreet delivery (sublingual liquid, one sip, no pills)
  • Tied for the highest price ($12 per dose)
Start My Free Evaluation

Free clinician review · Discreet packaging · Ships in 3-5 days

Effectiveness: Tester Notes

For ED treatments, timing matters. Most men want something that works quickly, without planning an hour ahead.

In testing, Taurus CHARGE and Ro Sparks were the fastest to take effect, with noticeable onset around 15 minutes. Hims Hard Mints and BlueChew Max both took 30 to 60 minutes.

All four claim effectiveness lasting up to 36 hours once active.

From David's testing journal

Day 4, Taurus."Took it under the tongue around 7pm, expecting nothing dramatic. By 7:15 there was the physical response, but also something I had not felt in a while: the actual wanting. Calm, present, switched on. My wife noticed too. Said something felt different. We did not talk about why."

Day 11, Ro Sparks."Worked. Slower start than Taurus, and I did not feel the same calm, just the physical effect. The tablet took noticeably longer to dissolve."

Day 19, Hims Hard Mints."Forty-five minutes before anything happened. By the time it kicked in, the moment had passed. The mint flavor was pleasant. The effect was milder."

Day 26, BlueChew Max."Similar to Hims. Chewable, slow onset, did the basics. Nothing surprised me, good or bad."

"What separated Taurus from the rest was not the erection. All four could do that on a good day. It was that I actually wanted to be there. The other three did one job. Taurus did two."
— David, 54

The PT-141 Difference

All four products contain sildenafil and tadalafil, two of the most clinically validated PDE5 inhibitors available. Together they handle the physical side of erectile function well.

But Taurus CHARGE is the only product in this comparison that also contains PT-141 (bremelanotide), a melanocortin peptide that works on the brain instead of the blood vessels. It is the ingredient that addresses the half of ED every other product on this list ignores.

1 in 3
men who did not respond to Viagra saw clinically significant results with PT-141 in a randomized, placebo-controlled trial (33.5% vs 8.5% on placebo).[1]

It is worth reading that twice. In a Journal of Urology study of 342 men whose ED had not responded to sildenafil, one in three got a clinically significant result from PT-141, roughly four times the placebo rate. These were men the blue pill had already failed.

Here is why it works when a pill alone does not. Sildenafil, tadalafil, and vardenafil all do the same thing: they relax blood vessels so blood can flow. If your issue is purely circulatory, that is enough. But for a lot of men, especially past 40, blood flow was never really the problem. Stress, pressure, and the natural dip in dopamine signaling can flatten arousal even when the plumbing works fine. That is the disconnect so many men describe and never have a word for: physically capable, mentally checked out.

PT-141 targets that exact gap. Instead of working on blood vessels, it activates melanocortin receptors in the brain, the same pathway your body uses to switch on desire in the first place.[4] It is a completely different mechanism from PDE5 inhibitors, which is why it reaches men that blood-flow drugs cannot. And the two work better together: in clinical testing, PT-141 combined with sildenafil produced a significantly stronger erectile response than sildenafil alone.[2] Hardware and software, finally in one dose.

"Most ED products only address blood flow. PT-141 works on the brain's arousal pathway, which is independent of the blood-flow mechanism entirely. For my patients who do not fully respond to PDE5 inhibitors, or who tell me the desire just is not there anymore, that is exactly the piece that has been missing."
— Dr. Marcus Hale, MD

Taurus CHARGE also includes vardenafil, the active medication in Levitra, a PDE5 inhibitor with faster onset and higher potency per milligram than sildenafil.[3] So even on the blood-flow side, the formula is carrying more firepower than a single-molecule pill.

One more thing worth knowing: PT-141 does not act on serotonin. For the many men whose low desire is a side effect of an antidepressant, it is one of the few options that can help without touching how their medication works. Ask the reviewing clinician if that is you.

Hims Hard Mints includes vitamin B12 as a support ingredient, but clinical evidence connecting B12 supplementation to improved erectile function is limited.

Bottom line: Taurus CHARGE is the only product here built to treat both halves of ED, the blood flow and the brain. Every other option is solving half the problem and hoping that is enough.

Start My Free Evaluation

Free clinician review · Discreet packaging · Ships in 3-5 days

Convenience and Side Effects

Taurus CHARGE pulls ahead on delivery. It comes in a small liquid ampoule that dissolves under the tongue in about a minute. It has a mild orange-citrus taste and is small enough to take discreetly, in a bathroom or hallway, without explanation.

Ro Sparks is also sublingual but uses a tablet that takes up to 10 minutes to dissolve, with a more bitter taste. Hims Hard Mints and BlueChew Max are chewable tablets, easier to recognize and less discreet in a social setting.

Side effects across the 30-day trial were minimal. David reported no adverse effects from any of the four. Sildenafil and tadalafil are associated with a low rate of mild side effects including flushing and indigestion.[3] PT-141 is generally well tolerated; the most commonly reported effects are mild nausea and flushing, and it can cause a temporary rise in blood pressure, which is why the clinician evaluation screens for cardiovascular history before approving it.[1]

Close-up of the Taurus CHARGE ampoule
Taurus CHARGE's ampoule dissolves under the tongue in about one minute.

Price and Value

Pricing varies across the four brands. Hims Hard Mints are the cheapest at about $7.50 per dose. BlueChew Max falls near $10. Ro Sparks and Taurus CHARGE are tied as the most expensive at around $12.

But in our trial, Hims Hard Mints also received the lowest tester score: slower onset, milder effect, and fewer active ingredients than the pricier options.

"You are paying for the active ingredients. With Hims, you are getting fewer of them."
— Dr. Marcus Hale, MD

Taurus CHARGE costs more, but it delivers four medications instead of two, including the only ingredient here that treats the mental side of arousal. For men whose ED never fully responded to a single-mechanism pill, that difference matters a lot more than $4.50.

One honest caveat: if the blue pill works well for you and timing has never been a problem, you probably do not need a four-in-one. Taurus CHARGE is built for the men it left wanting. If that is not you, save your money.

The Verdict

Our Final Recommendation

Taurus CHARGE

4.7 / 5

After 30 days, Taurus CHARGE was the only product we reviewed that treated both the physical and the mental side of erectile dysfunction. It had the fastest onset, the most complete formula, and the most discreet delivery of anything we tested, and it was the only one carrying a brain-level arousal ingredient, PT-141. For the men who have been let down by a pill that only ever solved half the problem, it was not close.

Best for: men who took the blue pill and found it only half-worked; men who want both speed and longevity in one dose; and anyone who wants something more discreet than a chewable tablet.

Editor's note on availability: Because Taurus CHARGE is compounded in small batches, demand has outpaced supply more than once in the past year. As of our last check it is back in stock, but we would start an evaluation sooner rather than later.
Start My Free Evaluation

Free clinician review · Discreet packaging · Ships in 3-5 days

Frequently Asked Questions

PT-141 (bremelanotide) is a peptide that works on the brain rather than the blood vessels. Standard ED pills like Viagra improve blood flow; PT-141 activates the melanocortin pathway your brain uses to trigger desire and arousal. Because it works through a completely different mechanism, it can help men who do not fully respond to blood-flow drugs alone. It is the ingredient that makes Taurus CHARGE a 4-in-1 rather than just another sildenafil-plus-tadalafil combo.

Viagra and Cialis are single-mechanism drugs. They relax blood vessels and nothing more. Taurus CHARGE includes those same blood-flow molecules (sildenafil, tadalafil, vardenafil) plus PT-141, which addresses arousal and desire in the brain. In short: the blue pill treats one cause of ED. Taurus treats two.

The active ingredients (sildenafil, tadalafil, vardenafil, and PT-141) are individually well-established medications. Taurus CHARGE is a compounded formulation prepared by US-licensed compounding pharmacies, which is common practice for combination ED treatments. Compounded medications are not individually FDA-approved as a single formula. PT-141 (bremelanotide) is FDA-approved as Vyleesi for sexual dysfunction in women and is prescribed off-label for men.

Most men report feeling effects within 10 to 15 minutes. The sublingual liquid format bypasses the digestive system, letting the medication enter the bloodstream faster than chewable or pill formats, which typically take 30 to 60 minutes.

Yes. Taurus requires a 2-minute online medical evaluation reviewed by a US-licensed clinician, typically within 24 hours. There is no in-person doctor visit required.

Taurus offers a satisfaction guarantee. If the standard formulation does not work for you, their clinical team can adjust the dose or formulation, or you can request a refund.

No. Taurus is a cash-pay telehealth service. There is no insurance billing, no entry on your pharmacy benefits record, and no in-person prescription pickup. All shipments arrive in unmarked packaging.

Moderate alcohol is generally considered compatible with PDE5 inhibitors, but you should discuss your specific situation with the reviewing clinician during your evaluation. Heavy alcohol use can interfere with both efficacy and safety.

About the Author and Reviewer

Sarah Chen
Sarah Chen
Editor-in-Chief, Trusted Ranking

Sarah covers prescription medications and telehealth for Trusted Ranking. She has 12 years of experience in health and consumer journalism, with prior bylines in Healthline, Self, and Consumer Reports.

Dr. Marcus Hale
Dr. Marcus Hale, MD
Primary Care Physician
Verified physician reviewer

Dr. Hale is a board-certified primary care physician with 15+ years of clinical experience. He completed his MD at the University of Michigan and his residency at Northwestern Memorial Hospital. He treats patients in Chicago and serves as a medical content reviewer for Trusted Ranking.

References

Last reviewed and updated: April 14, 2026

  1. 1.Safarinejad MR, Hosseini SY. Salvage of sildenafil failures with bremelanotide: a randomized, double-blind, placebo-controlled study. J Urol. 2008;179(3):1066-1071. https://pubmed.ncbi.nlm.nih.gov/18206919/
  2. 2.Diamond LE, Earle DC, Garcia WD, Spana C. Co-administration of low doses of intranasal PT-141, a melanocortin receptor agonist, and sildenafil to men with erectile dysfunction results in an enhanced erectile response. Urology. 2005;65(4):755-759. https://pubmed.ncbi.nlm.nih.gov/15833522/
  3. 3.Huang SA, Lie JD. Phosphodiesterase-5 (PDE5) inhibitors in the management of erectile dysfunction. P T. 2013;38(7):407-419. https://pubmed.ncbi.nlm.nih.gov/24049429/
  4. 4.Molinoff PB, Shadiack AM, Earle D, Diamond LE, Quon CY. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003;994:96-102. https://pubmed.ncbi.nlm.nih.gov/12851303/
  5. 5.Mayo Clinic. Erectile dysfunction: symptoms and causes. https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/symptoms-causes/syc-20355776